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PostPosted: 01/04/11 4:42 am • # 1 
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I had saved this article last week and then forgot to post it ~ I'll post the full story linked below next ~ it raises a LOT of questions in my own mind ~ both technical and ethical ~ Image ~ Sooz

British triplet born more than a decade after twin sisters -- any more coming?
12:02 p.m. CST, December 29, 2010

The British media is abuzz with news that a triplet was born 11 years after her twin sisters. It seems that, in the age of frozen embryos, all is possible.

The Daily Mail newspaper says experts proclaim the delayed birth to be a "record gap" for babies conceived at the same time via in vitro-fertilization. Twins Bethany and Megan Shepherd were born in Britain in 1998 and their remaining sister, Ryleigh, was born last month.

Apparently the Shepherds have more embryos from the same batch on ice, the
story says. And now they  face the same dilemma other IVF parents face: What to do with leftover embryos?

The
American Fertility Assn. offers this advice: "It's a private issue gone very public. It's a complex web of personal philosophy, religious orientation and social conscience about which everybody, and we mean everybody, has a strong opinion. But the fact is, and should be, what you do with the frozen embryos you don't use is your decision and yours alone." The options are limited to discarding the embryos, donating the embryos for research or donating to an infertile couple.

These guidelines from the
Centers for Disease Control and Prevention provide success rates and more information about assisted reproductive technology.

And this Los Angeles Times story
"On the cusp of life, and of law" examines the ethical and legal questions surrounding the issue.

http://www.chicagotribune.com/health/la ... 6018.story


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PostPosted: 01/04/11 4:58 am • # 2 
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Here's the story as reported in the British media ~ is this child a 'triplet' for her twin sisters? ~ will this child bear any ill effects given the length of time the embryo was frozen? ~ what are the ethical parameters here? ~ Sooz

Conceived together, born 11 years apart: Deep-frozen third sister arrives after record gap

By Lucy Laing
Last updated at 11:22 AM on 27th December 2010

It's hardly surprising that Ryleigh Shepherd is the image of her 11-year-old twin sisters when they were babies. For despite being born in different centuries, the three were all conceived on the same day.

While the embryos of twins Megan and Bethany were implanted in their mother in 1998, Ryleigh's was frozen for more than 11 years.

Experts say they know of no other case where three siblings from the same round of fertility treatment have been born with such an age gap.

‘When Ryleigh arrived she looked like both the girls did when they were born 11 years before,' said their mother Lisa, 37. ‘It was uncanny.'

Mrs Shepherd and husband Adrian, 45, married in 1994. They were keen to start a family but she had been diagnosed with endometriosis and polycystic ovaries so they knew their chances of her becoming pregnant naturally were slim.

‘I was given drug treatments to help me conceive, but nothing worked,' she said at the family home in Walsall. ‘It was devastating.'

In September 1998, the couple underwent treatment at Midland Fertility Clinic. Doctors collected 24 eggs, 14 of which were successfully fertilised with Mr Shepherd's sperm.

Two embryos were implanted and the remaining 12 placed into freezer storage.

Mrs Shepherd, a sales manager, said: ‘We knew there was a chance the treatment wouldn't work, so we tried not to get our hopes up.

‘I did a pregnancy test after a week which was negative. That was so disappointing. But a week later when the clinic did another test, it was positive.'

Scans showed Mrs Shepherd was expecting twins.

The pregnancy went smoothly and the twins were born by caesarean section at Walsall Manor Hospital, Megan weighing 4lb 4oz and Bethany 3lb 3oz.

Their mother said: ‘It was so emotional when they were born and even though they had been six weeks early they made a really good recovery and we were allowed to take them home just three days later.'

When the girls were nine, the couple started to consider another baby. ‘We had been so busy raising the twins that it wasn't until then that we stopped to think about having another one,' said Mrs Shepherd, whose husband is an engineer for Network Rail.

‘So we asked the girls what they thought about having another addition to the family and they really wanted it.'

In December 2009, the couple returned to Midland Fertility Clinic for another cycle of IVF, using the embryos stored ten years previously.

Mrs Shepherd said: ‘It seemed strange to think that we were using embryos that we had stored all those years ago, that were conceived at the same time as the girls. We knew that if we had another baby it would in effect be the girls' triplet as they were all conceived at the same time.

‘We didn't know if it would work, and we agreed that we would just have one go with one embryo and if it didn't work we wouldn't try again. It was one last chance, and if it was meant to be, then it would happen.' Ryleigh arrived last month, weighing a healthy 7lb 10oz.

Mrs Shepherd added: ‘The girls are thrilled to have a sister – and they know that she was conceived at the same time that they were, but has been in the freezer.

‘She's a really happy baby and has got a really good appetite – it's as though she's making up for lost time.'

http://www.dailymail.co.uk/health/article-1341766/Conceived-born-11-years-apart-Deep-frozen-sister-arrives-record-gap.html#ixzz19Q6hwoyf


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PostPosted: 01/04/11 7:13 am • # 3 
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this is a really interesting story. thanks for posting.


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PostPosted: 01/04/11 7:27 am • # 4 
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The story didn't say, but I assume that they are not identical twins or triplets. Nor did they say that the embryos were fertilized with the same sperm or if any of the 3 came from the same egg. THAT would be even weirder. If those conditions don't exist, one could essentially say that all siblings are twins, triplets etc. Just because they were conceived the same day means nothing really, imo. No more than a woman who has sex with two different men on the same day and conceives two embryos because she ovulated two eggs. That has happened as I'm sure this story has played out before. Perhaps with fewer years between births, but with the same batch of fertilized eggs. They just haven't been public knowledge.


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PostPosted: 01/04/11 11:46 am • # 5 
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I must correct myself. No two eggs could be fertilized by the same sperm.Image However, since the eggs are harvested, they really aren't twins if you consider that those eggs would have been ovulated at separate times naturally. If you get what I mean, lol.

In a related story:

Four women, one dad create 'twiblings' born days apart

http://today.msnbc.msn.co...oday-parenting?GT1=43001



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PostPosted: 01/04/11 12:17 pm • # 6 
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This is where I begin to question some of the ethics ~ I am delighted that fertility treatments have advanced to where infertile couples who want a child can have a biologic child ~ and I'm happy about legitimate surrogates, in cases where the mother is incapable of carrying a baby to term for whatever reason ~ but I have a significant problem with the 'designer' aspects ~ 

Sooz


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